Start of Main Content

Most common inpatient diagnosis-related group (DRG) codes

Mar 12th, 2025

By Maggy Bobek Tieché 2 min read
Most common inpatient diagnosis-related group (DRG) codes

While there has been a shift in care from hospitals to outpatient facilities like ambulatory surgery centers, inpatient services still account for about half of a hospital’s net patient revenue. Additionally, Medicare patients account for more than one-third of hospital payor days, on average. Understanding inpatient hospital stays is crucial for assessing patient populations, service line needs, and financial performance.

What is a DRG in healthcare?

Diagnosis-related groups (DRGs) are used to classify patients and document their hospital stay. Medicare sets a standard amount to pay for each hospital case and adds a payment weight for each DRG.

Medicare payment weights are based on several factors, including:

  • Case severity
  • Geographic location
  • Proportion of low-income patients in the hospital’s service area
  • Patient age, sex, and comorbidities

The Definitive Healthcare HospitalView product tracks Medicare inpatient DRGs for more than 5,800 U.S. hospitals. DRGs are sourced from the Medicare Standard Analytic Files (SAF).

How many DRGs are there?

The Definitive Healthcare HospitalView product includes 760 DRG codes for the 2024 calendar year. The table below highlights the top DRG codes for Medicare inpatients through June 2024, based on estimated payments. The year-to-date Medicare data comes from the 2024 Medicare Quarterly SAF, which reflects approximately 93% claims maturity for each quarter.

Top 10 most common DRGs for 2024

RankDRG codeDRG descriptionPercent of total DRG diagnoses
1871SEPTICEMIA OR SEVERE SEPSIS W/O MV 96 OR MORE HOURS W MCC4.7%
2177RESPIRATORY INFECTIONS & INFLAMMATIONS W MCC2.3%
3885PSYCHOSES2.1%
4003ECMO OR TRACH W MV 96 OR MORE HRS OR PDX EXC FACE, MOUTH & NECK W MAJ O.R.1.8%
5853INFECTIOUS & PARASITIC DISEASES W O.R. PROCEDURE W MCC1.7%
6291HEART FAILURE & SHOCK W MCC1.6%
7274PERCUTANEOUS INTRACARDIAC PROCEDURES W/O MCC1.4%
8790EXTREME IMMATURITY OR RESPIRATORY DISTRESS SYNDROME, NEONATE1.3%
9193SIMPLE PNEUMONIA & PLEURISY W MCC1.2%
10018CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL AND OTHER IMMUNOTHERAPIES1.1%

Fig 1. Data from Definitive Healthcare HospitalView product and sourced from the Medicare Quarterly Standard Analytic Files (SAF) for calendar year 2024. Accessed February 2025.

What is the most common DRG?

DRG code 871 (septicemia or severe sepsis) leads with 4.7% of estimated payments, followed by DRG code 177 (respiratory infections and inflammations) at 2.3%. Other notable codes include DRG 885 (psychoses) at 2.1% and DRG 003 (ECMO or trach with mechanical ventilation) at 1.8%. These top DRGs represent significant areas of inpatient care and can help identify trends in Medicare reimbursement.

Additional DRGs on the list include:

  • DRG 291: Heart failure and shock with major complications
  • DRG 274: Percutaneous intracardiac procedures without major complications
  • DRG 790: Extreme immaturity or respiratory distress syndrome in neonates
  • DRG 193: Simple pneumonia and pleurisy with major complications
  • DRG 018: CAR T-cell therapy and other immunotherapies

Looking for more DRG data? Explore the DRGs with the highest readmission rates or the top DRGs by diagnosis volume.

Learn more

Want to explore more on hospitals, healthcare systems, and physician groups? The Atlas Dataset from Definitive Healthcare is the foundation of our healthcare commercial intelligence, comprising multiple datasets to give you a longitudinal, comprehensive, and current picture of the healthcare market. Sign up for a free trial today.

Maggy Bobek Tieché

About the Author

Maggy Bobek Tieché

Maggy Bobek Tieché has worked with healthcare data for nearly 18 years. Her positions include roles in product management and custom reporting, working with life science,…

Author profile