New ICD-10 codes for 2025

Each year, the Centers for Medicare and Medicaid Services (CMS) and the National Center for Health Statistics (NCHS) publish reporting guidelines for the International Classification of Diseases (ICD), 10th revision, also known as ICD-10-CM. The guidelines are based on the World Health Organization’s (WHO) annual updates to the diagnosis lists.

How many new codes were added for 2025?

For 2025, 252 new codes were added, 36 codes were deleted, and 13 codes were revised. New codes are created to ensure the ICD system remains relevant and accurate as the field of medicine evolves. Meanwhile, code deletions and revisions occur to make corrections, add clarity, and facilitate expansions in certain code categories.

The WHO makes annual updates to the ICD-10 diagnosis list. In the U.S., the updated ICD-10-CM diagnosis codes take effect October 1st each year.

How are ICD codes classified?

ICD-10 codes are categorized into chapters based on body systems, medical conditions, and other factors. Each chapter represents a specific category of diseases or health-related issues, identified by an alphabetical letter (A-Z), followed by a numeric sequence.

Below, we’ve compiled a list of ICD-10 code changes by chapter using data from the CMS and the Atlas All-Payor Claims Dataset.