Cardiovascular, Renal, and Metabolism (CVRM)
What is Cardiovascular, Renal, and Metabolism (CVRM)?
Cardiovascular, renal, and metabolism, or CVRM, is the fastest-expanding disease spectrum worldwide. It links cardiovascular disease with its related comorbidities, such as diabetes, obesity, and chronic kidney disease.
CVRM focuses on the connections between:
- Heart failure
- Metabolism
- Kidney diseases
- Arteriopathies
CVRM diseases affect hundreds of millions of people around the world, and many people are living with two or even three of these chronic diseases. They can progress and cause further damage to vital organs along the way, making them debilitating and possibly life-threatening.
How is the cardiovascular, renal, and metabolism (CVRM) landscape changing?
Scientific research is evolving the current understanding of CVRM diseases and how they are connected. Knowing these connections can then pave the way for therapeutics that address risk factors impacting multiple CVRM diseases, improving health outcomes. New advances in CVRM include small interfering RNA and novel gene and cell therapies that can potentially regenerate vital organs.
The goal of CVRM treatment is to improve outcomes in a patient with a specific diagnosis before any comorbidities emerge, and this is accomplished by understanding the connections between diseases and finding ways to treat a disease that also lowers the risk of its comorbidities.